| Thursday, September 24 |
| 12:00-16:00 |
Arrival, registration |
| 16:00-16:10 | Jan Dohnálek - Introduction remarks |
| 16:10-16:30 | New groups |
| Chair: Pavlína Řezáčová, IOCB Prague |
| 16:30-16:45 |
Sven Dahms - Substrate Induced Activation of the Pro-Protein Convertase Furin |
postdoc |
| 16:45-17:00 |
Maria Rutkiewicz-Krotewicz - Psychrotrophic beta-D-galactosidase with unusual domains arrangement |
student |
| 17:00-17:15 |
Iuliia Iermak - Structural characterization of glyceraldehyde dehydrogenase from Thermoplasma acidophilum |
student |
| 17:15-17:30 |
Marta Grzechowiak - Crystal structure of inorganic pyrophosphatase from a higher plant |
student |
| 17:30-17:45 |
Leona Švecová - X-ray structure of Bilirubin oxidase form Myrothecium verrucaria with ligand in the active site |
student |
| 17:45-18:00 |
Tadeusz Skarzynski - Rigaku - Latest developments in equipment for diffraction and scattering from Rigaku Oxford Diffraction |
sponsor |
| 18:15-19:15 | Dinner |
| 19:30-20:30 | HEC lecture: Randy Read - Building software to get better structures faster: likelihood in Phaser |
| 21:00-??:?? (forever) | HEC Committee meeting & Bar |
| Friday, September 25 |
| 7:30 | Breakfast (at site of your accommodation) |
| Chair: Manuel Than, FLI Jena |
| 8:30-8:45 |
Bilal Muhammad Qureshi - Structural and Functional Analysis of Phytochrome Photoreceptors |
postdoc |
| 8:45-9:00 |
Oksana Degtjarik - Structural aspects of the specificity within the multistep phosphorelay signaling in plants |
postdoc |
| 9:00-9:15 |
Martje Kunz - Towards the structure of the Importin beta - Importin 7 complex |
student |
| 9:15-9:30 |
Sascha Walzer - Towards the Structure of HCMV pUL50/53 |
student |
| 9:30-9:45 |
Peter Kirchweger - Towards deciphering the structure of the SiiAB complex from Salmonella enterica, an integral membrane protein complex |
student |
| 9:45-10:00 |
Andreas Förster - Dectris - Pushing the limits of experimental phasing with new HPC detectors |
sponsor |
| 10:00-10:15 |
Jochen Mueller-Dieckmann - Formulatrix - Automation in Crystallization |
sponsor |
| 10:15-10:45 | Coffee break |
| Chair: Mariusz Jaskolski, CBB Poznan |
| 10:45-11:00 |
Piotr Wilk - Structure Analysis fo Human Prolidase Mutations gives insight into the Prolidase Deficiency disease mechanisms |
postdoc |
| 11:00-11:15 |
Aleš Hnízda - Hyperactivity of relapsed ALL-specific cN-II mutant is caused by affected allosteric regulation |
student |
| 11:15-11:30 |
Adéla Jílková - Activation and inhibition of SmCB1, an antiparasitic drug target |
student |
| 11:30-11:45 |
Martin Zühlsdorf - Dimerization-induced allosteric changes of the oxyanion-hole loop activate the pseudorabies virus assemblin pUL26N, a herpesvirus serine protease |
student |
| 11:45-12:00 |
Zora Nováková - Structural study of the complex of human glutamate carboxypeptidase II and hydroxamate-based inhibitors |
student |
| 12:00-12:15 |
Hervé-William Rémigy - FEI - CRYO-TEM: A third member joins the high resolution band |
sponsor |
| 12:15-12:30 |
Rachel Macmaster - Molecular Dimensions - Advances in protein crystallography |
sponsor |
| 12:30-13:30 | Lunch (Hotel U Kata) |
| 13:30-17:00 | Enjoying Kutna Hora / Mines excursions etc... |
| Chair: Wulf Blankenfeldt, HZI Braunschweig |
| 17:45-18:00 |
Julita Talaj - Anti-inflammatory drugs interactions with Ovine and Caprine Serum Albumins |
postdoc |
| 18:00-18:15 |
Franziska Huschmann - Crystallographic fragment-screening at the HZB MX-beamlines |
postdoc |
| 18:15-18:30 |
Ondřej Vaněk - Strategies for difficult targets: production of readily crystallizable glycoproteins in HEK293S GnTI- cell line, a case study of human lymphocyte receptors LLT1 and NKRP1 |
postdoc |
| 18:30-18:45 |
Marcin Kowiel - Protonation and geometry of His residues |
student |
| 18:45-19:00 |
Christin Reuter - Jena Bioscience - A new Thermofluor Design: Screens based on FUNDAMENTAL and SPECIFIC variables |
sponsor |
| 19:00-20:00 | Dinner (Hotel U Kata) |
| 21:00-... | Bar (Sponsored by Jena Bioscience) |
| Saturday, September 26 |
| 7:30 | Breakfast (at site of your accommodation) |
| Chair: Kristina Djinovic-Carugo, MFPL Vienna |
| 8:30-8:45 |
Martin Pannek - Characterization and modulation of mitochondrial Sirtuins 4 and 5 |
postdoc |
| 8:45-9:00 |
Anja Greschuchna - Structural analysis of YrdC, responsible for activation of the N6-threonylcarbamoyl moiety in t6A37 tRNA modification |
student |
| 9:00-9:15 |
Andrea Schmidt - The fine-tuned machinery of O2-tolerant [NiFe] hydrogenase |
postdoc |
| 9:15-9:30 |
Christian Feiler - Exploring the structural mechanisms of ubiquitination reactions |
postdoc |
| 9:30-9:45 |
Tobias Bock - Exploring unusual myxobacterial pathways- insights into the regulation of alternative isovaleryl-CoA biosynthesis |
student |
| 9:45-10:00 |
Vineet Gaur - Structure and mechanistic analysis of the Slx1-Slx4 endonuclease |
student |
| 10:00-10:30 | Coffee break |
| Chair: Udo Heinemann, MDC Berlin |
| 10:30-10:45 |
Marlena Kisiala - Structural studies of AvaII restriction endonuclease - RNA/DNA hybrid complex |
student |
| 10:45-11:00 |
Antonio Sponga - Structural characterization of the sarcomeric Z-disk FATZ:α-actinin-2 complex |
student |
| 11:00-11:15 |
Karolina Zielinska - Structural basis of non-muscle α-actinin regulation by calcium |
student |
| 11:15-11:30 |
Jan Driller - Structural studies on the synaptic active zone scaffold |
student |
| 11:30-11:45 |
Gert Weber - Structural studies on the selectivity of SNF binding to U1 and U2 snRNAs in Drosophila melanogaster |
student |
| 11:45-12:00 |
Peer Lukat - Griselimycins, Novel Anti Tuberculosis Agents: Structural Insights into the Mode of Action, Resistance and Biosynthesis |
postdoc |
| 12:00-12:15 |
Michal Szczepek - Crystal structure of a common GPCR-binding interface for G protein and arrestin |
postdoc |
| 12:15-12:30 |
HEC prize and concluding remarks |
| 12:30-13:30 | Lunch (Hotel U Kata) |